Cissus Quadrangularis Extract has been shown to offer a number of benefits including improved joint health, increased bone strength, and possibly weight loss. Our Cissus Super Extract contains 150 capsules at a 1,000mg serving size of two capsules. Studies have shown that anywhere from 500mg – 3,000mg taken daily is safe and may offer many benefits such as reduced joint pain and improved bone strength. Our cissus supplement is manufactured in the USA (Eaglewood, New York) and tested in the USA by a cGMP FDA approved company. We offer a 100% money back guarantee for all unsatisfied customers.